:root{color-scheme:dark light;--bg: #020617;--bg-alt: #020617;--card: #020617;--border: rgba(148, 163, 184, .4);--accent: #38bdf8;--accent-soft: rgba(56, 189, 248, .12);--accent-strong: #0ea5e9;--text: #e5e7eb;--muted: #9ca3af;--danger: #f97373;--radius-lg: 18px;--radius-xl: 24px;--shadow-soft: 0 18px 45px rgba(15, 23, 42, .75);--max-width: 1120px}*,*:before,*:after{box-sizing:border-box}html{font-family:system-ui,-apple-system,BlinkMacSystemFont,SF Pro Text,sans-serif;background:radial-gradient(circle at top,#0f172a 0,#020617 45%,#000);color:var(--text)}body{margin:0;min-height:100vh}a{color:var(--accent);text-decoration:none}a:hover{color:var(--accent-strong);text-decoration:underline}.page-shell{min-height:100vh;display:flex;flex-direction:column}.page-inner{width:100%;max-width:var(--max-width);margin:0 auto;padding:1.5rem 1.25rem 3rem}.site-header{display:flex;align-items:center;justify-content:space-between;gap:1rem;padding:1.25rem 1.25rem .5rem}.site-header-inner{width:100%;max-width:var(--max-width);margin:0 auto;display:flex;align-items:center;justify-content:space-between;gap:1rem}.brand{display:flex;align-items:center;gap:.75rem}.brand-mark{width:32px;height:32px;border-radius:999px;background:radial-gradient(circle at 30% 30%,#38bdf8 0,#0ea5e9 35%,#1e293b 75%,#020617);border:1px solid rgba(148,163,184,.6);box-shadow:0 0 0 1px #0f172acc,0 20px 40px #0f172ae6}.brand-text{display:flex;flex-direction:column}.brand-text span:first-child{font-weight:600;letter-spacing:.04em}.brand-text span:last-child{font-size:.75rem;color:var(--muted)}.nav-links{display:flex;align-items:center;gap:1rem;font-size:.9rem}.nav-links a{color:var(--muted);text-decoration:none}.nav-links a:hover{color:var(--accent-strong)}.nav-cta{border-radius:999px;padding:.4rem .9rem;border:1px solid rgba(148,163,184,.5);background:radial-gradient(circle at top left,rgba(56,189,248,.18),transparent 55%);color:var(--text);font-size:.8rem}.shell-main{flex:1}.hero-grid{display:grid;grid-template-columns:minmax(0,2.2fr) minmax(0,2fr);gap:1.5rem;margin-top:1rem}@media (max-width: 768px){.hero-grid{grid-template-columns:minmax(0,1fr)}.site-header-inner{flex-direction:column;align-items:flex-start}}.hero-card,.panel-card{background:radial-gradient(circle at top left,var(--accent-soft),transparent 60%),#0f172af2;border-radius:var(--radius-xl);border:1px solid var(--border);box-shadow:var(--shadow-soft);padding:1.5rem;position:relative;overflow:hidden}.hero-card:before{content:"";position:absolute;inset:0;background:radial-gradient(circle at 0 0,rgba(56,189,248,.16),transparent 55%),radial-gradient(circle at 100% 100%,rgba(94,234,212,.16),transparent 55%);opacity:.9;mix-blend-mode:screen;pointer-events:none}.hero-card-inner{position:relative;z-index:1}.hero-eyebrow{font-size:.75rem;text-transform:uppercase;letter-spacing:.18em;color:var(--muted);margin-bottom:.5rem}.hero-title{font-size:clamp(1.9rem,3vw,2.4rem);line-height:1.05;letter-spacing:.02em;margin-bottom:.75rem}.hero-title span{background:linear-gradient(120deg,#7dd3fc,#22c55e);-webkit-background-clip:text;color:transparent}.hero-subtitle{font-size:.95rem;color:var(--muted);max-width:36rem;margin-bottom:1.25rem}.hero-footer{display:flex;flex-wrap:wrap;gap:.75rem;align-items:center;margin-top:.75rem}.chip{display:inline-flex;align-items:center;gap:.4rem;padding:.3rem .75rem;border-radius:999px;border:1px solid rgba(148,163,184,.5);background:#0f172ae6;font-size:.75rem;color:var(--muted)}.chip-dot{width:6px;height:6px;border-radius:999px;background:#22c55e}.mono{font-family:ui-monospace,SFMono-Regular,Menlo,Monaco,Consolas,Liberation Mono,Courier New,monospace}.secondary-card-header{display:flex;align-items:center;justify-content:space-between;gap:.75rem;margin-bottom:1rem}.secondary-card-header h2{font-size:.95rem;text-transform:uppercase;letter-spacing:.16em;color:var(--muted)}.secondary-chip-row{display:flex;flex-wrap:wrap;gap:.5rem}.metric-pill{display:inline-flex;align-items:center;gap:.35rem;padding:.25rem .6rem;border-radius:999px;background:#0f172ad9;border:1px dashed rgba(148,163,184,.5);font-size:.75rem;color:var(--muted)}.content-section{margin-top:2rem;display:grid;gap:1.5rem}.section-heading{display:flex;align-items:center;justify-content:space-between;gap:.75rem}.section-heading h2{font-size:1rem;letter-spacing:.12em;text-transform:uppercase;color:var(--muted)}.section-heading p{font-size:.85rem;color:var(--muted);max-width:28rem}.card-row{display:grid;grid-template-columns:repeat(auto-fit,minmax(260px,1fr));gap:1.25rem}.panel-card h3{font-size:1rem;margin-bottom:.4rem}.panel-card p{font-size:.9rem;color:var(--muted)}.drug-list{list-style:none;padding:0;margin:.75rem 0 0;display:flex;flex-wrap:wrap;gap:.4rem}.drug-list a{font-size:.8rem;padding:.18rem .55rem;border-radius:999px;border:1px solid rgba(148,163,184,.4);background:#0f172ae6;text-decoration:none}.form-row{display:grid;gap:.75rem;margin-bottom:1rem}@media (min-width: 640px){.form-row{grid-template-columns:repeat(2,minmax(0,1fr))}}.field{display:flex;flex-direction:column;gap:.25rem;font-size:.85rem}.field label{color:var(--muted)}.field input,.field select{background:#0f172af2;border-radius:999px;border:1px solid rgba(148,163,184,.6);color:var(--text);padding:.4rem .8rem;font-size:.9rem;outline:none}.field input:focus,.field select:focus{border-color:var(--accent-strong);box-shadow:0 0 0 1px #38bdf866}.metric-row{display:flex;flex-wrap:wrap;gap:.75rem;margin-top:.5rem;font-size:.8rem;color:var(--muted)}.metric-row strong{color:var(--text)}.chart-shell{margin-top:1rem;border-radius:1rem;border:1px solid rgba(148,163,184,.4);background:radial-gradient(circle at top,#0f172ae6,#020617);padding:.75rem}.chart-shell svg{width:100%;height:160px}.badge{display:inline-flex;align-items:center;gap:.3rem;font-size:.75rem;padding:.16rem .55rem;border-radius:999px;background:#0f172ae6;border:1px solid rgba(148,163,184,.6);color:var(--muted)}.badge-pill{width:5px;height:5px;border-radius:999px;background:#818cf8}.search-box{margin-top:.75rem}.search-box input{width:100%;border-radius:999px;border:1px solid rgba(148,163,184,.6);padding:.45rem .85rem;background:#0f172ae6;color:var(--text);font-size:.9rem}.search-results{margin-top:.6rem;max-height:220px;overflow:auto}.search-results ul{list-style:none;padding:0;margin:0}.search-results li a{display:block;padding:.25rem .1rem;font-size:.85rem;color:var(--text);text-decoration:none}.search-results li a span{color:var(--muted);font-size:.75rem}.footer{border-top:1px solid rgba(30,64,175,.7);padding:1.25rem 1.25rem 2rem;margin-top:auto}.footer-inner{max-width:var(--max-width);margin:0 auto;display:flex;flex-wrap:wrap;gap:.75rem;justify-content:space-between;font-size:.75rem;color:var(--muted)}.footer-inner a{color:var(--muted)}.table{width:100%;border-collapse:collapse;margin-top:.75rem;font-size:.85rem}.table th,.table td{border-bottom:1px solid rgba(31,41,55,.9);padding:.4rem .2rem}.table th{text-align:left;font-weight:500;color:var(--muted)}