HalfLifeDB Drug half-life explorer

Half-life profile

Caffeine half-life calculator

Estimate how much Caffeine remains in your body over time using a first-order elimination model. Values are approximate and should not replace lab testing or medical advice.

Now estimated in body: 3.59 mg(3.6% of starting amount)Half-life used: 5 h

Pharmacokinetics at a glance

Mean half-life 5 hours

Typical detection windows

Detection windows are approximate and depend on dose, frequency, metabolism, specimen cutoffs and lab methods.

Matrix Window
blood Typically detectable for many hours after consumption; concentrations decline over roughly a day in most adults.
urine Metabolites can be detectable for at least 1 day, depending on dose and kidney function.

How this model treats Caffeine

The calculator uses a simple one-compartment model with first-order elimination. Every half-life, the remaining amount is halved. Real-world pharmacokinetics can be more complex (multi-compartment models, active metabolites, saturable metabolism).

Medically reviewed sources

  1. Bonati M. Pharmacology of caffeine. In: Caffeine. Springer (book chapter hosted on NCBI Bookshelf).

Notes

This page is for educational and informational purposes only. It does not provide medical or legal advice and does not tell you whether you are safe to drive, work or pass a drug test.