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Substance categories

Categories are editorial navigation groups. They help readers compare curve shapes without implying a clinical recommendation, legal status, safety ranking, or shared risk profile.

What categories are for

HalfLifeDB categories help readers find related profiles and compare the representative half-life values used by the calculators. They are deliberately humble labels: useful for browsing, too blunt for decision making.

A category can contain substances with very different routes, metabolites, formulations, and study evidence. This directory keeps those small groups together instead of creating thin category pages. Open the individual profile when you need source links, checkpoint tables, and notes about uncertainty.

How to compare entries

Compare half-life values only after checking what the value represents. A parent compound, metabolite, terminal phase, effective half-life, or formulation-specific estimate can answer different questions. HalfLifeDB uses one representative value per profile so the educational curve stays readable.

The site does not use categories to suggest use, purchase, dosing, testing, or safety decisions. The educational focus is pharmacokinetic interpretation: what a simple curve shows, where it breaks down, and where source context should be checked.

Navigation group

antidepressant

2 reviewed profiles currently published.

SubstanceRepresentative half-lifeSources
Sertraline26 h3
Fluoxetine4.0 days3

Navigation group

benzodiazepine

2 reviewed profiles currently published.

SubstanceRepresentative half-lifeSources
Alprazolam11.2 h3
Diazepam30 h3

Navigation group

dissociative

1 reviewed profile currently published.

SubstanceRepresentative half-lifeSources
Ketamine2.5 h4

Navigation group

entactogen

1 reviewed profile currently published.

SubstanceRepresentative half-lifeSources
MDMA8 h5

Navigation group

gabapentinoid

1 reviewed profile currently published.

SubstanceRepresentative half-lifeSources
Gabapentin6 h3

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opioid

2 reviewed profiles currently published.

SubstanceRepresentative half-lifeSources
Morphine2 h4
Oxycodone3.5 h4

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opioid treatment

2 reviewed profiles currently published.

SubstanceRepresentative half-lifeSources
Methadone24 h3
Buprenorphine37 h3

Navigation group

psychedelic

3 reviewed profiles currently published.

SubstanceRepresentative half-lifeSources
DMT10 min3
Psilocybin3 h3
LSD3.6 h4

Navigation group

stimulant

3 reviewed profiles currently published.

SubstanceRepresentative half-lifeSources
Cocaine1 h4
Nicotine2 h3
Caffeine5 h3

Navigation group

wakefulness promoting

1 reviewed profile currently published.

SubstanceRepresentative half-lifeSources
Modafinil15 h4