Per-substance profiles
Each substance has a dedicated page with a half-life calculator, a brief explanation of the model, and links to sources.
PK-aware tools
Drug half-life made visual.
Choose a substance and a time since dose. HalfLifeDB estimates how much remains under a simple first-order elimination model using published half-life estimates.
Search 50+ substances
research, Rx, everydayStart with something common like MDMA, cocaine, THC, caffeine, or explore benzodiazepines, opioids and more. Each entry links to a dedicated half-life page.
Browse: all drugs · categories · knowledge
- 2C-B
- Alcohol · Ethanol
- Alprazolam · Xanax
- Amphetamine
- Ayahuasca · DMT + MAOI brew
- Caffeine
- CBD · Cannabidiol
- Clonazepam · Klonopin
- Clonidine
- Cocaine
- Codeine
- Diazepam · Valium
- DMT · N,N-Dimethyltryptamine
- Dextromethorphan · DXM
- Etizolam
- Fentanyl
- Gabapentin
- GBL · Gamma-butyrolactone
- 1,4-Butanediol · 1,4-BD
- GHB · Gamma-hydroxybutyrate
- Heroin · Diacetylmorphine
- Hydrocodone
- Ketamine
- Kratom · Mitragynine
- Codeine-promethazine syrup · Purple drank, Lean
- Lorazepam · Ativan
- LSD
- MDA
- MDMA · Ecstasy, Molly
- MDMB-class synthetic cannabinoids
- Mephedrone · 4-MMC
- Methamphetamine · Meth
- Methylphenidate · Ritalin
- Modafinil
- Morphine
- MXE · Methoxetamine
- Nicotine
- Nitrous oxide · Laughing gas, N2O
- Norketamine
- Oxycodone
- PCP · Phencyclidine
- Phenibut
- Pregabalin
- Psilocybin · Magic mushrooms
- Tapentadol
- THC · Delta-9-tetrahydrocannabinol
- Tianeptine
- Tramadol
- Zolpidem · Ambien
- Zopiclone / Eszopiclone
What HalfLifeDB does
HalfLifeDB is for educational use only. It visualizes how a simple half-life model behaves over time. It is not a diagnostic tool and does not substitute for professional medical advice.
Simple elimination curves
The calculator applies a one-compartment first-order elimination model. Every half-life interval, the model halves the remaining amount and plots the curve.