About HalfLifeDB
HalfLifeDB is an educational product focused on making substance half-life concepts easier to understand. It provides interactive graphs for simple first-order elimination models together with curated profile pages, source links, and plain-language interpretation.
The site is maintained as an independent reference project at HalfLifeDB.co. It is not an online pharmacy, treatment provider, recovery program, laboratory testing service, or marketplace. The content is written to explain pharmacokinetic concepts and point readers toward source material, not to encourage substance use or replace professional judgment.
The goal is to help people visualize relative first-order decline using published pharmacokinetic half-life values. It is not a body-concentration or diagnostic tool and does not estimate impairment, legal fitness to drive, or fitness for medical procedures.
How the calculator works
The calculator assumes a single-compartment, first-order elimination model using a single half-life value. This is a simplification. Many substances have multi-compartment kinetics, active metabolites, or non-linear behavior that are not reflected here.
Because of this, the curves on this site should be treated as approximate visualizations only. Real-world concentrations in blood, urine, and other matrices depend on many factors including dose, route of administration, individual metabolism, liver and kidney function, and drug interactions.
What makes the site useful
A half-life value is easy to quote but harder to defend. HalfLifeDB pairs supported values with curves, checkpoints, and source context. When the evidence is indirect or the substance is a mixture or class, the site leaves the curve out and explains why.
The project also separates concept articles from individual substance profiles. If you are new to the topic, start with the evidence guides or the methodologypage before relying on any one profile.
Who maintains the content
HalfLifeDB is maintained as an independent educational reference. Profile pages connect every displayed model to source links, calculator assumptions, and explicit safety boundaries. They should not be treated as clinical guidance.
Each substance profile lists its latest update date and links to references used for follow-up reading. If a citation is indirect, preclinical, or included for context rather than as a direct human half-life estimate, that limitation is described near the reference.
The public data and evidence inventory lists every supported curve, its representative model, reported range, reference count, and latest update date. The profile libraryalso includes source notes for substances that do not yet have a defensible numerical model.
Content boundaries
HalfLifeDB avoids dosing instructions, purchase information, drug-testing evasion, instructions for misuse, or individualized medical advice. Profiles are written around pharmacokinetic interpretation: what half-life means, why estimates differ, and how to read a simple curve.
Corrections
If a page appears incomplete or inaccurate, send the page URL and supporting source toadmin@halflifedb.co. See theresearch standards for publication criteria and theupdate history for current profile dates.
Disclaimer
HalfLifeDB does not provide medical, legal, or treatment advice. Always consult a licensed medical professional for questions about medication use, substance use, dosing, or health decisions.