HalfLifeDB Drug half-life explorer

Half-life profile

Cocaine half-life calculator

Estimate how much Cocaine remains in your body over time using a first-order elimination model. Values are approximate and should not replace lab testing or medical advice.

Now estimated in body: 0.00 mg(0.0% of starting amount)Half-life used: 1 h

Pharmacokinetics at a glance

Mean half-life 1 hours

Typical detection windows

Detection windows are approximate and depend on dose, frequency, metabolism, specimen cutoffs and lab methods.

Matrix Window
blood Usually detectable for several hours and up to ~1 day after use in occasional users.
urine Parent drug and metabolites often detectable for 1–3 days; heavy use can extend this window.
saliva Frequently detectable up to about 24–48 hours after use.
hair Can be detectable for months, depending on hair length and pattern of use.

How this model treats Cocaine

The calculator uses a simple one-compartment model with first-order elimination. Every half-life, the remaining amount is halved. Real-world pharmacokinetics can be more complex (multi-compartment models, active metabolites, saturable metabolism).

Medically reviewed sources

  1. Bravo RR et al. Cocaine: an updated overview on chemistry, detection and analysis (2022).
  2. Scheidweiler KB et al. Pharmacokinetics of cocaine and metabolites in human oral fluid (2010).

Notes

This page is for educational and informational purposes only. It does not provide medical or legal advice and does not tell you whether you are safe to drive, work or pass a drug test.