HalfLifeDB Drug half-life explorer

Half-life profile

MDMA half-life calculator

Estimate how much MDMA remains in your body over time using a first-order elimination model. Values are approximate and should not replace lab testing or medical advice.

Now estimated in body: 12.50 mg(12.5% of starting amount)Half-life used: 8 h

Pharmacokinetics at a glance

Mean half-life 8 hours

Typical detection windows

Detection windows are approximate and depend on dose, frequency, metabolism, specimen cutoffs and lab methods.

Matrix Window
blood Typically up to ~24 hours after use in occasional users; longer with heavy or repeated dosing.
urine Often detectable for 1–3 days in occasional users; longer in heavy or chronic use.
saliva Roughly up to 24–48 hours after use in most studies.
hair May be detectable for 1–3 months or longer depending on hair length and use pattern.

How this model treats MDMA

The calculator uses a simple one-compartment model with first-order elimination. Every half-life, the remaining amount is halved. Real-world pharmacokinetics can be more complex (multi-compartment models, active metabolites, saturable metabolism).

Medically reviewed sources

  1. Kolbrich EA et al. Pharmacokinetics of MDMA in humans (2008).
  2. Irvine RJ et al. Plasma drug concentrations and physiological measures in MDMA users (2006).

Notes

This page is for educational and informational purposes only. It does not provide medical or legal advice and does not tell you whether you are safe to drive, work or pass a drug test.