HalfLifeDBEvidence before certainty.

25I-NBOMe evidence profile

The available records identify 25I-NBOMe and document toxicological concern, but they do not supply controlled human concentration-time data from which a typical half-life can be selected.

Category: psychedelic · Updated: August 7, 2026

Sources and model notes are maintained by . This page is educational, not clinical guidance. Corrections: admin@halflifedb.co.

Model statusNo curve publishedCurrent sources do not support one defensible human input
Evidence boundarySource note onlyNo animal, forensic, mixture, or proxy value is presented as a human half-life
Model scopeNot modeledThe profile explains what the available records can and cannot establish
References2Linked studies, labels, reviews, or identity records described below

25I-NBOMe: evidence and interpretation notes

Why HalfLifeDB does not plot 25I-NBOMe

The available records identify 25I-NBOMe and document toxicological concern, but they do not supply controlled human concentration-time data from which a typical half-life can be selected. A toxicology overview is not a pharmacokinetic cohort.

What each source contributes

  • PubChem: 25I-NBOMe. This identity record confirms names and compound identity and does not supply a human half-life.
  • 2C-I-NBOMe, an “N-bomb” that kills with “Smiles”. Toxicological and legislative aspects. This supporting literature record adds compound-specific background and is used only within the limits of its design.

For 25I-NBOMe, the decision to withhold a curve turns on the limits visible in 2C-I-NBOMe, an “N-bomb” that kills with “Smiles”. Toxicological and legislative aspects. This supporting literature record adds compound-specific background, but it is used only within the limits of its design.

What evidence would change the page

The publication threshold for a future 25I-NBOMe model is concrete: serial human plasma data, explicit analyte identification, a described route or preparation, and a reported half-life phase. 2C-I-NBOMe, an “N-bomb” that kills with “Smiles”. Toxicological and legislative aspects remains useful, but it does not cross that threshold.

InterpretationCategory context and evidence limits

psychedelic context

Psychedelic duration is shaped by pharmacodynamics as well as pharmacokinetics, so subjective effects may not track a simple elimination curve.

  • The curve does not predict psychological effects or functional safety.
  • Metabolites and downstream receptor activity are not separately modeled.
  • Published estimates may come from small or specialized study populations.
EvidenceSource trail and model decision

Sources and evidence context

A linked record is not automatically proof of the displayed value. Study, labeling, review, and compound identity sources serve different purposes; notes below identify limitations when they are known.

1 PubMed0 PMC0 DailyMed1 PubChem
  1. Identity record PubChem Compound Summary: 25I-NBOMe.
    Compound identity and naming record. It supplies chemistry context, not independent numerical support for the model.
  2. Research abstract PubMed: 2C-I-NBOMe, an "N-bomb" that kills with "Smiles". Toxicological and legislative aspects.
    Supporting literature record. Its role and study design should be read from the linked source before applying any numerical finding.
BoundariesWhat this page cannot answer and where to continue

What this page does not answer

  • It does not estimate impairment, intoxication, or fitness to drive.
  • It does not predict urine, blood, saliva, or hair test results.
  • It does not model repeated exposure, tolerance, withdrawal, or interactions.
  • It does not replace clinician, pharmacist, toxicologist, or emergency guidance.

Continue with context

Read the medical disclaimer, methodology, and research standards before using the model for comparison.